Between June and December 1522, the Ottoman military besieged the island of Rhodes in an attempt to take dispel the Knights of Rhodes from the island, and to consolidate their control of the Mediterranean. After months of fighting, Rhodes eventually accepted Suleiman’s terms of surrender and the remaining Knights were allowed to leave the island.
https://greekcitytimes.com/2021/06/26/on-this-day-siege-of-rhodes-1522/